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Ferrohumate-containing preparation and prospects of its use in veterinary medicine

Abstract

   Inorganic and organic salts of iron, as well as its complex compounds with dextrins and various polymers are widely used in animal breeding for the treatment and prevention of anemia. Means for prevention and treatment of anemia in animals can be created on the base of iron complexes with humic substances. Technological parameters of peat oxidation have been established, in the process of which there is a significant increase in the amount of oxygen-containing functional groups in the composition of humic acids. The method of introduction of iron ions into liquid humic preparation was developed. Freshly prepared iron (III) hydroxide obtained by interaction of iron (III) chloride with sodium hydroxide was used as an iron-containing compound. Preliminary evaluation of the therapeutic efficacy of ferrohumate-containing preparation on laboratory animals against experimental iron deficiency anemia showed that it contains iron assimilable by ane animal body, capable of binding to blood proteins and being included in the processes of hematopoiesis. Oral administration of ferrogumate to white rats for 5 days at the rate of 0.7 mg of iron per head per day activates the hematopoietic system of animals. Oral administration of ferrogumate to white rats for 10 days (two courses of 5 days with an interval of 2 days) at the same dose increases iron reserves and levels the manifestation of experimental iron deficiency anemia, which is confirmed by the results of laboratory blood tests.

About the Authors

N. A. Zhmakova
Institute of Nature Management of the National Academy of Sciences of Belarus
Belarus

Nadezhda A. Zhmakova, Ph. D. (Technical), Associate Professor, Leading Researcher

220076; 10, F. Skoriny Str.; Minsk



N. L. Makarova
Institute of Nature Management of the National Academy of Sciences of Belarus
Belarus

Natalyia L. Makarova, Ph. D. (Technical), Associate Professor, Senior Researcher

220076; 10, F. Skoriny Str.; Minsk



M. P. Kuchinsky
S. N. Vyshelessky Institute of Experimental Veterinary Science
Belarus

Mikhail P. Kuchinsky, D. Sc. (Veterinary), Professor, Chief Researcher

220063; 28, Briketa Str. Minsk



G. M. Kuchinskaya
S. N. Vyshelessky Institute of Experimental Veterinary Science
Belarus

Galina M. Kuchinskaya, Researcher, Acting Head of the department

220063; 28, Briketa Str.; Minsk



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For citations:


Zhmakova N.A., Makarova N.L., Kuchinsky M.P., Kuchinskaya G.M. Ferrohumate-containing preparation and prospects of its use in veterinary medicine. Nature Management. 2024;(1):164-175. (In Russ.)

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ISSN 2079-3928 (Print)